Niacinamide: What It Does and How to Use It

Updated August 2026 · 2 min read · Written against published cosmetic research

Niacinamide (also called Vitamin B3 or nicotinamide) is one of the most versatile and well-tolerated skincare ingredients available. It works across virtually every skin type and concern — which is why you’ll find it in everything from serums to moisturisers to SPFs.

What Is Niacinamide?

Niacinamide is a water-soluble form of Vitamin B3. Unlike many active ingredients that target one specific problem, niacinamide functions as a multi-tasker — addressing everything from oil control to barrier repair, making it a rare ingredient that genuinely suits all skin types.

Key Benefits of Niacinamide

  • Minimises pores — reduces the appearance of enlarged pores by regulating sebum and tightening skin around pores
  • Controls oil — helps regulate sebum production, making it ideal for oily and combination skin
  • Fades dark spots — inhibits the transfer of melanin to skin cells, gradually lightening hyperpigmentation
  • Strengthens the skin barrier — boosts ceramide production, helping skin retain moisture and resist irritants
  • Reduces redness — anti-inflammatory properties calm rosacea, sensitivity, and post-acne redness
  • Smooths skin texture — regular use improves overall skin clarity and softness

What Concentration Should You Use?

Niacinamide is effective at concentrations between 2% and 10%. For most people, 5% is the sweet spot — effective for pores, oil control, and brightening without the risk of irritation that very high concentrations can occasionally cause. If you have sensitive skin, start at 2–5%. The 10% concentrations (like The Ordinary’s Niacinamide 10% + Zinc 1%) are excellent for oily, acne-prone skin.

How to Layer Niacinamide

One of niacinamide’s great advantages is its layering flexibility. Apply it after cleansing and toning, before heavier serums and moisturisers. It can be used morning and evening.

Does niacinamide conflict with Vitamin C? The concern that mixing them causes skin flushing is largely a myth based on outdated research. Modern formulations are stable at skin-friendly pH levels, and using both (even in the same routine) is generally fine. If you want to be cautious, use your Vitamin C serum in the morning and niacinamide at night.

Best Niacinamide Combinations

Niacinamide pairs beautifully with:

  • Hyaluronic acid — for hydration + barrier repair
  • Zinc — enhances oil control and anti-inflammatory effects (common in the same formulation)
  • Retinol — niacinamide helps counteract retinol’s drying effects when used together
  • Peptides — complementary support for skin firmness and barrier function

Who Is Niacinamide Best For?

Virtually everyone. It’s particularly impactful for oily and combination skin types concerned about pores and shine, anyone dealing with acne marks or uneven skin tone, sensitive skin that can’t tolerate stronger actives, and mature skin looking to support barrier function alongside anti-aging ingredients.

Top Niacinamide Products

The Ordinary Niacinamide 10% + Zinc 1% is the cult favourite for good reason — affordable, effective, and widely available. Paula’s Choice 10% Niacinamide Booster is excellent for layering. For a luxe option, The INKEY List Niacinamide Serum delivers 10% niacinamide at a very accessible price point.

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